Key result
Blood flow index using NIRS and ICG strongly correlated with work of breathing (R2=0.863-0.887, P<0.001) and EMG (R2=0.879-0.930, P<0.001) in respiratory muscles.
Why the study?
Does blood flow index (BFI) using NIRS and ICG accurately reflect respiratory muscle blood flow compared to work of breathing and EMG in healthy humans?
Population
7 healthy humans
Authors
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BFI may support noninvasive RMBF assessment in research; leaves open validation in patients before clinical use.
Cross-Sectional (n=7)
Does blood flow index (BFI) using NIRS and ICG accurately reflect respiratory muscle blood flow compared to work of breathing and EMG in healthy humans?
Effect estimate: R2 0.863 to 0.930
p-value: p=<0.001
BFI using NIRS and ICG is a valid, minimally invasive method to assess respiratory muscle blood flow in humans.
Guenette et al. (2011) conducted a cross-sectional in Healthy (n=7). Blood flow index (BFI) using near-infrared spectroscopy and indocyanine green vs. Work of breathing and electromyography (EMG) was evaluated on Correlation of BFI with work of breathing and electromyography (EMG) (R2 0.863 to 0.930, p=<0.001). Blood flow index using NIRS and ICG strongly correlated with work of breathing (R2=0.863-0.887, P<0.001) and EMG (R2=0.879-0.930, P<0.001) in respiratory muscles.
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