Key result
Near-infrared spectroscopy with indocyanine green quantified peak exercise calf muscle blood flow (74+/-5 ml/100ml/min) similarly to dye dilution (77+/-6 ml/100ml/min).
Why the study?
Does near-infrared spectroscopy with indocyanine green accurately measure regional blood flow during exercise in humans compared to established methods?
Observational
Does near-infrared spectroscopy with indocyanine green accurately measure regional blood flow during exercise in humans compared to established methods?
NIRS combined with ICG provides a valid, high-resolution method for quantifying regional tissue blood flow during exercise in humans.
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NIRS-ICG may enable noninvasive exercise perfusion assessment; leaves open clinical validation before practice adoption.
Boushel et al. (2000) reported an observational. Near-infrared spectroscopy (NIRS) and indocyanine green (ICG) vs. Dye dilution with MRI and (133)Xe washout was evaluated on Blood flow in calf muscle and around the Achilles tendon during plantar flexion. Near-infrared spectroscopy with indocyanine green quantified peak exercise calf muscle blood flow (74+/-5 ml/100ml/min) similarly to dye dilution (77+/-6 ml/100ml/min).