Key result
In patients with LV dysfunction, pulmonary artery end-diastolic pressure correlated with wedge pressure (r=0.92, P<0.001) but failed to accurately represent LV end-diastolic pressure.
Why the study?
Does pulmonary artery end-diastolic pressure accurately reflect left ventricular end-diastolic and mean filling pressures in patients with and without left ventricular dysfunction?
Population
71 subjects undergoing cardiac catheterization, including 15 with normal left ventricular function and 56…
Design
Cross-sectional
Authors
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PA a-wave pressure may estimate LVEDP better than PAEDP in LV dysfunction; leaves open prospective validation before clinical use.
Observational (n=71)
Does pulmonary artery end-diastolic pressure accurately reflect left ventricular end-diastolic and mean filling pressures in patients with and without left ventricular dysfunction?
Effect estimate: r = 0.92
p-value: p=<0.001
In patients with LV dysfunction, PAEDP does not accurately reflect LVEDP, but the PA a wave pressure closely estimates LVEDP unless pulmonary vascular resistance is markedly elevated.
Falicov et al. (1970) conducted an observational in Left ventricular dysfunction (n=71). Left ventricular dysfunction vs. Normal left ventricular function was evaluated on Correlation between pulmonary artery end-diastolic pressure and left ventricular end-diastolic pressure (r = 0.92, p=<0.001). In patients with LV dysfunction, pulmonary artery end-diastolic pressure correlated with wedge pressure (r=0.92, P<0.001) but failed to accurately represent LV end-diastolic pressure.
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