July 1, 1975Journal of the American Geriatrics Society
Left Ventricular Filling Pressures in Cardiac Patients†
Key result
Pulmonary artery wedge pressure correlated well with left ventricular end-diastolic pressure in patients with coronary disease (r=0.84) and non-coronary disease (r=0.81).
Why the study?
How do pulmonary artery end-diastolic pressure and pulmonary artery wedge pressure correlate with left ventricular diastolic pressures in patients with and without coronary disease?
Population
94 cardiac patients, including 51 with coronary disease and 43 with non-coronary disease.
Design
Cross-sectional
Authors
Discussion
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Implication
Caution against equating PADP with LVEDP in coronary disease; Level 5 data leaves open need for modern validation.
Study Design
Type
Observational (n=94)
Structured PICO
How do pulmonary artery end-diastolic pressure and pulmonary artery wedge pressure correlate with left ventricular diastolic pressures in patients with and without coronary disease?
P
Population
94 cardiac patients (51 with coronary disease and 43 with non-coronary disease, excluding mitral stenosis) evaluated for left ventricular filling pressures.
E
Exposure
Measurement of pulmonary artery end-diastolic pressure (PADP), pulmonary artery wedge pressure (PAWP), pre-"a" wave left ventricular diastolic pressure (LVDP), and post-"a" wave left ventricular end-diastolic pressure (LVEDP).
O
Outcome
Correlation between PADP, PAWP, LVDP, and LVEDP.surrogate
Pulmonary artery end-diastolic pressure and pulmonary artery wedge pressure correlate well with left ventricular diastolic pressures, suggesting they are useful for evaluating left ventricular function at the bedside.
Cite This Study
Prakash et al. (1975) conducted an observational in Cardiac disease (coronary and non-coronary) (n=94). Pulmonary artery end-diastolic pressure (PADP) and pulmonary artery wedge pressure (PAWP) vs. Left ventricular diastolic pressures (LVDP and LVEDP) was evaluated on Correlation between right-sided and left-sided filling pressures. Pulmonary artery wedge pressure correlated well with left ventricular end-diastolic pressure in patients with coronary disease (r=0.84) and non-coronary disease (r=0.81).