Happy new YerE: The first example of the title reaction is presented using a ThDP-dependent enzyme catalyst. The substrate tolerance of the enzyme is very broad and includes cyclic and open-chain ketones, as well as diketones and α- and β-ketoesters as acceptor substrates. The absolute configurations of two enzymatic products were determined by single-crystal structure analysis.
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Lehwald et al. (2010) studied this question.
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