Key result
A pharmacist-managed inpatient anticoagulation service significantly increased the percentage of INRs achieving therapeutic range within 5 days compared to standard care (88% vs 38%, P<0.001).
Why the study?
Does a pharmacist-managed inpatient anticoagulation service improve INR control in patients newly started on warfarin?
Population
170 patients newly started on warfarin for deep vein thrombosis, pulmonary embolism or atrial fibrillation…
Comparison
Pharmacist-managed inpatient anticoagulation… vs Standard care.
Design
Cohort
Follow-up
Until hospital discharge
Authors
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May support pharmacist consultation for new warfarin starts; leaves open confirmation in randomized trials.
Cohort (n=170)
No
Does a pharmacist-managed inpatient anticoagulation service improve INR control in patients newly started on warfarin?
Absolute Event Rate: 88% vs 38%
p-value: p=<0.001
Implementation of a pharmacist-managed inpatient anticoagulation service significantly improved the efficiency and safety of warfarin initiation compared to standard care.
Wong et al. (2010) conducted a cohort in Deep vein thrombosis, pulmonary embolism or atrial fibrillation (n=170). Pharmacist-managed inpatient anticoagulation service vs. Standard care (baseline period) was evaluated on percentage of international normalized ratios (INRs) achieving therapeutic range within 5 days (p=<0.001). A pharmacist-managed inpatient anticoagulation service significantly increased the percentage of INRs achieving therapeutic range within 5 days compared to standard care (88% vs 38%, P<0.001).
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