Key result
Pharmacist-led anticoagulation monitoring significantly increased the percentage of time within the target INR range compared to usual care (73.20% vs 46.32%, P<0.001) in hospitalized patients receiving warfarin.
Why the study?
The study was conducted to investigate the role of a pharmacist-led anticoagulation monitoring service for warfarin therapy in patients during hospitalization.
Does daily pharmacist-led anticoagulation monitoring improve the effectiveness and safety of warfarin in hospitalized patients?
Population
421 patients receiving warfarin anticoagulation therapy during hospitalization
Comparison
Daily pharmacist-led anticoagulation monitoring service vs warfarin therapy without pharmaceutical care
Design
Retrospective cohort study
Follow-up
During hospitalization
Authors
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May support pharmacist involvement in warfarin care; hypothesis-generating and should not yet change practice without RCTs.
Cohort (n=421)
No
Does daily pharmacist-led anticoagulation monitoring improve the effectiveness and safety of warfarin in hospitalized patients?
Absolute Event Rate: 73.2% vs 46.32%
p-value: p=<0.001
Pharmacist-led anticoagulation monitoring during hospitalization may improve the effectiveness and safety of warfarin therapy.
Huang et al. (2020) conducted a cohort in Patients requiring warfarin anticoagulation therapy (n=421). Pharmacist-led anticoagulation monitoring vs. Usual care without pharmaceutical care was evaluated on Percentage time within target INR range (TTR) (p=<0.001). Pharmacist-led anticoagulation monitoring significantly increased the percentage of time within the target INR range compared to usual care (73.20% vs 46.32%, P<0.001) in hospitalized patients receiving warfarin.
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