Key result
In patients with left bundle branch block, impaired left ventricular ejection fraction was an independent determinant of interventricular activation delay (beta = -0.58; P<0.0001).
Population
75 patients with left bundle branch block, comprising 42 with dilated cardiomyopathy and 33 with normal…
Comparison
Pulsed Doppler myocardial imaging (DMI) vs Patients with LBBB and normal global LV systolic…
Design
Cross-sectional
Authors
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Dyssynchrony severity tracks LV size and EF in LBBB; leaves open whether DMI improves CRT selection.
Cross-Sectional (n=75)
Effect estimate: beta coefficient = -0.58
p-value: p=< 0.0001
Pulsed Doppler myocardial imaging effectively quantifies regional activation delay in LBBB, demonstrating that interventricular dyssynchrony is strongly driven by LV dilatation and global systolic dysfunction.
Caso et al. (2006) conducted a cross-sectional in Left bundle branch block (n=75). Impaired left ventricular ejection fraction (dilated cardiomyopathy) vs. Normal global left ventricular systolic function was evaluated on Interventricular activation delay (beta coefficient = -0.58, p=< 0.0001). In patients with left bundle branch block, impaired left ventricular ejection fraction was an independent determinant of interventricular activation delay (beta = -0.58; P<0.0001).
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