A Comparative Study of Angiographic Severity of Coronary Artery Disease in Diabetic and Non-Diabetic Patients with Acute Coronary Syndrome by Gensini Scoring System

BACKGROUND is enough evidence that the presence of diabetes increases the risk of atherosclerotic disease from two-fold to three-fold, with coronary artery (CAD) as its chief sequelae. We wanted to study the type of vessels, of vessels, severity of lesions involving coronary artery and its branches patients with ACS and compare the involvement in diabetic and non-diabetic with ACS by Gensini scoring system. 144 Patients (72 diabetics and 72 nondiabetics) with acute coronary syndrome by clinical examination, ECG and or/ cardiac enzyme levels, admitted in of KIMS Hospital, Hubli, and undergoing coronary angiography during the period were included in the study as per the inclusion and exclusion criteria. patient was evaluated with history taking, clinical examination, and lab (ECG, 2D-Echo, coronary angiography, HbA1c, lipid profile and renal test). Based on angiographic findings, coronary artery disease severity calculated using Gensini, and the data obtained was analysed by different methods. of 144 patients, ACS was commoner among males than females (72.9% vs. 27.1%) and age of presentation was earlier in males compared to females (53 yrs. . 58 yrs.). Multivessel disease was commoner in diabetics compared to nondiabetics (52.8% vs. 15.3%) and also mean Gensini score was higher in diabetics (45.2 vs. 19.2). this study we can conclude that diabetic patients with ACS have more severe disease with respect to higher number of vessels involved, more severe and higher Gensini score and also severity increases with the duration diabetes and poor glycaemic control.