Key result
Implantable cardioverter defibrillator insertion significantly decreased the rate of sudden cardiac death (p = 0.02) but showed no significant difference in overall survival (p = 0.25) compared to standard medical treatments.
Why the study?
The authors sought to clarify concerning points regarding the survival benefits of ICD insertion in patients with nonischemic dilated cardiomyopathy.
Does implantable cardioverter defibrillator insertion improve overall survival and reduce sudden cardiac death in patients with nonischemic dilated cardiomyopathy compared to standard medical therapy alone?
Cohort
Does implantable cardioverter defibrillator insertion improve overall survival and reduce sudden cardiac death in patients with nonischemic dilated cardiomyopathy compared to standard medical therapy alone?
p-value: p=0.25
In patients with nonischemic dilated cardiomyopathy, the addition of an ICD to standard medical therapy reduces sudden cardiac death but may not significantly improve overall survival.
Our previous study aimed to investigate overall survival (OS) and sudden cardiac death (SCD) variables in nonischemic dilated cardiomyopathy (DCM) patients treated only with standard medical treatments versus those who received implantable cardioverter defibrillator (ICD) in addition to routine medical treatments. Our findings revealed no significant difference in OS between the two groups (p = .25), but a significant decrease in SCD rate due to ICD insertion (p = .02). Furthermore, we found no significant difference between the two groups concerning baseline characteristics and type of medical treatments received. We attempted to answer and clarify the concerning points regarding the survival benefits of ICD insertion in nonischemic DCM patients that were mentioned.
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Omran et al. (2023) conducted a cohort in Nonischemic dilated cardiomyopathy. Implantable cardioverter defibrillator (ICD) vs. Standard medical treatments only was evaluated on Overall survival (OS) (p=0.25). Implantable cardioverter defibrillator insertion significantly decreased the rate of sudden cardiac death (p = 0.02) but showed no significant difference in overall survival (p = 0.25) compared to standard medical treatments.
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