Key result
Pregnancy in women with osteogenesis imperfecta was associated with severe back pain in 13.1% of pregnancies, often related to vertebral crush fractures.
Why the study?
What is the likelihood of musculo-skeletal problems during or just after pregnancy in women with osteogenesis imperfecta?
Population
100 women with osteogenesis imperfecta who had 213 pregnancies between 1957 and 1998
Design
Cross-sectional
Authors
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Alerts to fracture risk in OI pregnancies; leaves open whether caesarean delivery modifies outcomes.
Observational (n=100)
What is the likelihood of musculo-skeletal problems during or just after pregnancy in women with osteogenesis imperfecta?
Women with osteogenesis imperfecta have a notable risk of severe back pain and vertebral fractures during or after pregnancy, prompting recommendations to avoid prolonged breast feeding.
McAllion et al. (2002) conducted an observational in Osteogenesis imperfecta (n=100). Pregnancy was evaluated on Severe back pain in or after pregnancy. Pregnancy in women with osteogenesis imperfecta was associated with severe back pain in 13.1% of pregnancies, often related to vertebral crush fractures.
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