Key result
New echovirus 11 variant linked to severe sepsis and ~300% more fatal neonatal enterovirus infections.
Population
Nine neonates with severe infections caused by a new variant of echovirus 11
Design
Case series
Authors
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May warrant neonatal echovirus surveillance; case report leaves open need for prospective confirmation.
Observational (n=9)
Absolute Event Rate: 1.6% vs 0.4%
A new variant of echovirus 11 is circulating in France, causing severe and fatal neonatal infections characterized by sepsis and liver failure, warranting national and international alerts.
Grapin et al. (2023) conducted an observational in Severe neonatal infections (n=9). New variant of echovirus 11 vs. 2016-2021 period was evaluated on Fatal neonatal enterovirus infections. A new variant of echovirus 11 caused severe neonatal sepsis and liver failure, with fatal neonatal enterovirus infections increasing to 1.6% in 2022-2023 compared to 0.4% in 2016-2021.