Key result
Perinatal transmission of echovirus 11 resulted in fatal disease characterized by progressive hepatic failure and generalized bleeding in four premature infants lacking passively acquired maternal antibody.
Population
4 premature infants with fatal echovirus 11 disease during a community outbreak in Massachusetts in 1979
Design
Case_series
Follow-up
up to 6+ days
Authors
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Warrants clinical vigilance for echovirus 11 in antibody-deficient premature neonates; leaves open questions on prevention strategies.
Case Report (n=4)
Fatal echovirus 11 in premature neonates can present with severe hepatic failure and bleeding, likely driven by perinatal transmission before the development of protective maternal antibodies.
John F. Modlin (1980) conducted a case report in Echovirus 11 disease (n=4). Perinatal transmission of echovirus 11 was evaluated on Clinical course and mortality. Perinatal transmission of echovirus 11 resulted in fatal disease characterized by progressive hepatic failure and generalized bleeding in four premature infants lacking passively acquired maternal antibody.
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