What question did this study set out to answer?

This review aims to summarize cases and outbreaks of neonatal echovirus infection, highlighting disease severity and transmission dynamics.

Perinatal Echovirus Infection: Insights from a Literature Review of 61 Cases of Serious Infection and 16 Outbreaks in Nurseries

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Literature review identifies severe echovirus infections in infants, revealing implications for transmission and outcomes.

This review aims to summarize cases and outbreaks of neonatal echovirus infection, highlighting disease severity and transmission dynamics.
Literature review of echovirus infections published before June 1985, focusing on 61 cases and 16 outbreaks.
Analysis of infection timing, transmission routes, and maternal health preceding neonatal cases.
70% of cases were due to echovirus 11, with higher mortality in severe hepatitis (83%) compared to CNS infections (19%).
Attack rates during nursery outbreaks ranged from 22%-52%, mostly resulting in mild disease, with 12% mortality among nosocomially infected infants.
Infections often occur in the immediate perinatal period, with severe cases typically arising from maternal infections.

John F. Modlin (1986) studied this question.

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