Key result
BADL disability linked to ~96% higher hip fracture risk, partially driven by depressive symptoms.
Why the study?
The relationship between Activities of Daily Living (ADL) disability and hip fracture incidence in middle-aged and older adults, and the potential mediating role of depressive symptoms, remained unclear.
Does ADL disability increase the incidence of hip fractures in middle-aged and older adults, and is this mediated by depression?
Population
5,066 middle-aged and older adults in China without baseline hip fractures
Comparison
ADL functional capacity categorized by IADL and BADL
Design
Longitudinal analysis of CHARLS cohort data
Follow-up
Four-year
Authors
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Assessing BADL disability may stratify hip fracture risk in older adults; leaves open whether targeting depressive symptoms prevents fractures.
Cohort (n=12,642)
Yes
Does ADL disability increase the incidence of hip fractures in middle-aged and older adults, and is this mediated by depression?
Odds Ratio: 1.96 (95% CI 1.47–2.61)
p-value: p=<0.001
ADL disability independently predicts hip fractures in older Chinese adults, with depressive symptoms mediating a substantial portion of this risk.
Li et al. (2025) conducted a cohort in Hip fractures (n=12,642). Basic Activities of Daily Living (BADL) disability vs. Normal BADL function was evaluated on Incidence of hip fractures (OR 1.96, 95% CI 1.47-2.61, p=<0.001). Basic Activities of Daily Living (BADL) disability significantly increased the risk of incident hip fractures (OR 1.96) in older Chinese adults, with depressive symptoms mediating 23.4% of this effect.
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