Key result
Antioxidant vitamin intake was not associated with coronary artery calcification, but the highest quartile of vitamin E was linked to increased calcification (OR 1.77; 95% CI 1.02-3.06).
Why the study?
Does antioxidant vitamin intake prevent coronary artery calcification in adults without known coronary artery disease?
Population
865 consecutive patients, 39-45 years of age, 83% male, without known coronary artery disease, presenting…
Comparison
Antioxidant vitamin intake vs Lower levels of antioxidant vitamin intake
Design
Cross-sectional
Authors
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No association with early CAC in asymptomatic adults cautions against routine antioxidant use; leaves open prospective effects on progression.
Cross-Sectional (n=865)
Does antioxidant vitamin intake prevent coronary artery calcification in adults without known coronary artery disease?
Odds Ratio: 1.77 (95% CI 1.02–3.06)
Antioxidant vitamin intake does not prevent early coronary atherosclerosis, and high doses of vitamin E may be associated with increased calcification risk.
Hatzigeorgiou et al. (2006) conducted a cross-sectional in Subclinical coronary atherosclerosis (n=865). Antioxidant vitamin intake vs. Lower intake was evaluated on Coronary artery calcification (OR 1.77, 95% CI 1.02-3.06). Antioxidant vitamin intake was not associated with coronary artery calcification, but the highest quartile of vitamin E was linked to increased calcification (OR 1.77; 95% CI 1.02-3.06).
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