Key result
Higher blood HbA1c levels were significantly associated with increased risks of target vessel revascularization progression (OR 1.36; 95% CI 1.03-1.82) and nonfatal MI in diabetic patients after PCI.
Why the study?
Are higher HbA1c levels associated with worse clinical outcomes in diabetic patients after PCI?
Population
3,290 diabetic patients after percutaneous coronary intervention (PCI) pooled from 8 studies
Comparison
Higher HbA1c levels vs Lower HbA1c levels
Design
Meta-analysis
Authors
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May warrant closer post-PCI HbA1c monitoring in diabetes; extends observational evidence on revascularization and MI risk without mortality benefit.
Meta-Analysis (n=3,290)
Are higher HbA1c levels associated with worse clinical outcomes in diabetic patients after PCI?
Odds Ratio: 1.36 (95% CI 1.03–1.82)
Higher HbA1c levels in diabetic patients undergoing PCI are associated with an increased risk of target vessel revascularization and nonfatal myocardial infarction, highlighting the importance of glycemic control.
Zheng et al. (2016) conducted a meta-analysis in Diabetes mellitus after percutaneous coronary intervention (n=3,290). Higher HbA1c levels vs. Lower HbA1c levels was evaluated on Target vessel revascularization progression (OR 1.36, 95% CI 1.03-1.82). Higher blood HbA1c levels were significantly associated with increased risks of target vessel revascularization progression (OR 1.36; 95% CI 1.03-1.82) and nonfatal MI in diabetic patients after PCI.
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