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July 20, 2023CNS Neuroscience & TherapeuticsOpen Access

Transcranial pulse stimulation in Alzheimer's disease

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Authors

XCXinxin ChenJYJiuhong YouHMHui Ma

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Overview

Systematic review investigates the effects of transcranial pulse stimulation on cognitive and depressive symptoms in Alzheimer's disease, suggesting potential benefits.

Key Points

  • This review aims to assess the effects and safety of transcranial pulse stimulation (TPS) in treating Alzheimer's disease.
  • Systematic review of studies from multiple databases including PubMed and Cochrane Library.
  • Data extraction and quality evaluation performed independently by two reviewers.
  • Methodological Index for Nonrandomized Studies used for risk of bias assessment.
  • TPS significantly improved cognitive performance on multiple tests including CERAD (p<0.05).
  • TPS reduced depressive symptoms, reflected by lower scores on the Alzheimer's Disease Assessment Scale (affective) (p<0.05).
  • Adverse events were mild and reversible, with no serious complications observed.

Cite This Study

Chen et al. (2023) studied this question.

synapsesocial.com/papers/6a5f79f25fa505cbb76069c8https://doi.org/10.1111/cns.14372
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Also Consider

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  1. 1Transcranial Pulse Stimulation in Alzheimer’s: Long-Term Feasibility and a Multifocal Treatment Approach2025
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  4. 4Electrical brain networks before and after transcranial pulsed shockwave stimulation in Alzheimer’s patients2024 · 10 citations
  5. 5602. RESEARCH ON TRANSCRANIAL PULSE STIMULATION (TPS) IN MAJOR DEPRESSIVE DISORDER (MDD)2025