What type of study is this?

This is a Human Clinical Trial study.

September 16, 2025European PsychiatryOpen Access

Neuronavigated Transcranial Pulse Stimulation (TPS) with shock waves as a novel tool of noninvasive brainstimulation (NIB) for a long-term treatment of Alzheimer’s disease

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Authors

USUlrich SprickSt. Josef Krankenhaus AGAli Riza GünesSt. Alexius Heart and Lung Clinic MBM. V. Beglau

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Implication

Neuronavigated transcranial pulse stimulation improved cognitive performance and mood in Alzheimer's patients, indicating its potential as a therapeutic option.

Key Points

TPS stimulation significantly improved Stroop-Test performance in patients with Alzheimer's disease after 6 sessions.
The mean score of the Stroop-Test decreased from pre-treatment, indicating enhanced executive function (p < 0.05).
Mood improvement was also evident, with BDI scores dropping from 20.1 at baseline to 9.1 after treatment.
No severe side effects were reported throughout the treatment sessions, highlighting the safety of TPS.

Cite This Study

Sprick et al. (2025) studied this question.

synapsesocial.com/papers/68d454cb31b076d99fa5a4c1 https://doi.org/10.1192/j.eurpsy.2025.558

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Implication

Neuronavigated transcranial pulse stimulation improved cognitive performance and mood in Alzheimer's patients, indicating its potential as a therapeutic option.

Neuronavigated Transcranial Pulse Stimulation (TPS) with shock waves as a novel tool of noninvasive brainstimulation (NIB) for a long-term treatment of Alzheimer’s disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Neuronavigated Transcranial Pulse Stimulation (TPS) with shock waves as a novel tool of noninvasive brainstimulation (NIB) for a long-term treatment of Alzheimer’s disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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