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September 10, 2025Brain SciencesOpen Access

Transcranial Pulse Stimulation in Alzheimer’s: Long-Term Feasibility and a Multifocal Treatment Approach

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Authors

CCCeline Cont-RichterNSNathalie StuteAGAnastasia Galli

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Overview

Observational analysis shows cognitive benefits in Alzheimer’s patients receiving transcranial pulse stimulation, suggesting potential for broader treatment applications.

Key Points

  • TPS demonstrated significant improvement in cognitive assessments among Alzheimer's patients after one year.
  • Adverse events were minimal, occurring in less than 1% of sessions, mainly involving mild pain or transient sensations.
  • Regular psycho-neuro assessments showed lasting effects in areas like memory, speech, and mood after initial stimulation.
  • Careful patient selection and monitoring are crucial to ensure safety and effectiveness of TPS as a treatment option.

Cite This Study

Cont-Richter et al. (2025) studied this question.

synapsesocial.com/papers/68c1b81854b1d3bfb60ec2f8https://doi.org/10.3390/brainsci15080830
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Also Consider

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  1. 1Transcranial pulse stimulation in Alzheimer's disease2023 · 23 citations
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  4. 4Transcranial pulse stimulation modulates spectral signatures of Alzheimer’s disease in the 3×Tg-AD mouse model2026
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