Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 16, 2025European PsychiatryOpen Access

New therapeutic option for treatment-resistant depression using transcranial pulse stimulation: real-world data from a case series

View Full Paper
Ask AI
Bookmark
Share

Authors

AGAli Riza GünesMBM. BeglauMKMartin Köhne

Discussion

Loading...

Member takes

Overview

Case series evaluates transcranial pulse stimulation's effectiveness in reducing depressive symptoms, suggesting a new option for treatment-resistant depression.

Key Points

  • All patients showed a reduction in depressive symptoms, with the mean Beck Depression Inventory score decreasing from 41 to 26.
  • Five patients participated in the treatments, receiving a total of six transcranial pulse stimulation sessions over two weeks.
  • The study utilized neuro-navigation to precisely apply pulses to key brain regions associated with depression, including the nucleus accumbens.
  • Transcranial pulse stimulation appears to be a well-tolerated treatment option, with no significant side effects reported during or after treatment.

Cite This Study

Günes et al. (2025) studied this question.

synapsesocial.com/papers/68d4507d31b076d99fa57ffahttps://doi.org/10.1192/j.eurpsy.2025.555
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcranial Pulse Stimulation (TPS) suitable add-on treatment of patients with psychiatric disorders?2025
  2. 2602. RESEARCH ON TRANSCRANIAL PULSE STIMULATION (TPS) IN MAJOR DEPRESSIVE DISORDER (MDD)2025
  3. 3Prefrontal Transcranial Pulse Stimulation for Major Depressive Disorder2026
  4. 4Antidepressant effect of transcranial pulse stimulation (TPS) targeting neuropsychiatric disorders: a retrospective analysis.2026 · 1 citations
  5. 5Neuronavigated Transcranial Pulse Stimulation (TPS) with shock waves as a novel tool of noninvasive brainstimulation (NIB) for a long-term treatment of Alzheimer’s disease2025