What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Type 2 diabetes mellitus (n=150). Intervention: Co-morbid hypertension vs. No co-morbid hypertension. Primary outcome: Elevated 10-year CVD risk (≥ 10%) (AOR 4.69, 95% CI 1.81-12.19, p=0.002).

July 22, 2026Discover Endocrinology and MetabolismOpen Access

Patterns and determinants of cardiovascular disease risk in type 2 diabetes mellitus: insights from a tertiary care centre in Nigeria

Q: What are the key findings of this study?

Co-morbid hypertension (AOR 4.69; 95% CI 1.81-12.19) and longer diabetes duration (AOR 1.26) were significant determinants of elevated 10-year cardiovascular risk in patients with type 2 diabetes.

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Key result

Hypertension is linked to ~4.7-fold higher 10-year CVD risk in type 2 diabetes.

AOR 4.69
95% CI 1.81-12.19
P=0.002
n=150

Population

150 randomly selected type 2 diabetes mellitus patients receiving specialized diabetes care at a tertiary…

Design

Cross-sectional

Authors

JMJamila Aminu MohammedNile University of Nigeria BBBruno BasilEnugu State University of Science and Technology INIzuchukwu NnachiNile University of Nigeria

Discussion

Member takes

Implication

A significant proportion of T2DM patients in specialized care in Nigeria have elevated 10-year CVD risk, driven primarily by longer diabetes duration and comorbid hypertension.

Key Points

This research aims to understand the patterns and determinants of cardiovascular disease risk in patients with type 2 diabetes mellitus in Nigeria.
Hospital-based cross-sectional study among 150 randomly selected T2DM patients.
Data collected included demographic, clinical, and biochemical information using structured proforma.
Binary logistic regression was used to identify significant determinants of cardiovascular disease risk.
57.3% of participants had low cardiovascular disease risk (< 10%), while 42.7% had elevated risk (≥ 10%).
Longer duration of diabetes significantly increased CVD risk (AOR = 1.26, 95% CI: 1.15–1.39; p < 0.001).
The presence of co-morbid hypertension was also a significant determinant (AOR = 4.69, 95% CI: 1.81–12.19; p = 0.002).

Study Design

Type

Cross-Sectional (n=150)

Multicenter

Structured PICO

Population

150 randomly selected patients with type 2 diabetes mellitus receiving specialized diabetes care at a tertiary care centre in Nigeria.

Outcome

10-year cardiovascular disease (CVD) risk assessed using updated World Health Organization (WHO) laboratory-based CVD risk assessment chartsurrogate

Main Result

Odds Ratio: 4.69 (95% CI 1.81–12.19)

p-value: p=0.002

A significant proportion of T2DM patients in specialized care in Nigeria have elevated 10-year CVD risk, driven primarily by longer diabetes duration and comorbid hypertension.

Cite This Study

Mohammed et al. (2026) conducted a cross-sectional in Type 2 diabetes mellitus (n=150). Co-morbid hypertension vs. No co-morbid hypertension was evaluated on Elevated 10-year CVD risk (≥ 10%) (AOR 4.69, 95% CI 1.81-12.19, p=0.002). Co-morbid hypertension (AOR 4.69; 95% CI 1.81-12.19) and longer diabetes duration (AOR 1.26) were significant determinants of elevated 10-year cardiovascular risk in patients with type 2 diabetes.

synapsesocial.com/papers/6a605dfa4163e025518d7e95 https://doi.org/10.1007/s44417-026-00017-4

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Implication

A significant proportion of T2DM patients in specialized care in Nigeria have elevated 10-year CVD risk, driven primarily by longer diabetes duration and comorbid hypertension.

Patterns and determinants of cardiovascular disease risk in type 2 diabetes mellitus: insights from a tertiary care centre in Nigeria

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Patterns and determinants of cardiovascular disease risk in type 2 diabetes mellitus: insights from a tertiary care centre in Nigeria

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider