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September 5, 2025BMC Endocrine DisordersOpen Access

Beyond blood pressure and glucose: exploring potential biochemical predictors of cardiovascular disease risk in patients with type 2 diabetes mellitus and co-morbid hypertension

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Cross-sectional analysis reveals no significant predictors of CVD risk in hypertensive T2DM patients, suggesting limitations of traditional markers.

Patients with T2DM and hypertension showed significantly higher levels of hsCRP and AIP, indicating potential biochemical predictors.
The estimated WHO CVD risk scores were significantly elevated in hypertensive patients, with 60% classified as moderate-to-high risk.
Despite elevated biochemical markers, only hsCRP and AIP were assessed but did not emerge as significant independent predictors post-adjustment.
This highlights the need for improved early risk assessment strategies and aggressive blood pressure control in affected populations.

Basil et al. (2025) studied this question.

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Cross-sectional analysis reveals no significant predictors of CVD risk in hypertensive T2DM patients, suggesting limitations of traditional markers.