Key result
The cumulative incidence of infective endocarditis after Melody valve implantation ranged from 3.2% to 25.0%, with death or reintervention higher in non-streptococcal IE (73% vs 30%, P=0.001).
Why the study?
What is the incidence and natural history of infective endocarditis after transcatheter pulmonary valve implantation with the Melody valve?
Systematic Review (n=851)
What is the incidence and natural history of infective endocarditis after transcatheter pulmonary valve implantation with the Melody valve?
Infective endocarditis is a significant complication after Melody valve implantation, occurring at an annualized rate of 1.3% to 9.1% and frequently requiring surgical or transcatheter reintervention.
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High mortality and reintervention after IE post-TPVI warrant vigilance; leaves open optimal prevention strategies.
Abdelghani et al. (2018) conducted a systematic review in Infective endocarditis after transcatheter pulmonary valve implantation (n=851). Transcatheter pulmonary valve implantation with the Melody valve was evaluated on Incidence of infective endocarditis. The cumulative incidence of infective endocarditis after Melody valve implantation ranged from 3.2% to 25.0%, with death or reintervention higher in non-streptococcal IE (73% vs 30%, P=0.001).
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