Key result
An 8-week in-home virtual reality program (RelieVRx) was superior to an active sham for reducing pain intensity (MD 0.406; 95% CI 0.170-0.642) and pain interference at day 56.
Why the study?
To determine whether an 8-week self-administered in-home virtual reality program is superior to active sham for improving pain intensity and interference in chronic low back pain.
Does an 8-week in-home virtual reality program improve pain intensity and pain interference in adults with chronic low back pain?
Population
1067 adults with nonmalignant chronic low back pain for at least 3 months
Comparison
In-home behavioral skills virtual reality program (RelieVRx) vs active sham
Design
Randomized sham-controlled trial
Follow-up
Day 56
Authors
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May support in-home VR as a nonpharmacologic pain option; extends randomized evidence for digital therapeutics.
RCT (n=1,067)
Sham-controlled
1:1
Yes
Does an 8-week in-home virtual reality program improve pain intensity and pain interference in adults with chronic low back pain?
Mean Difference: 0.406 (95% CI 0.17–0.642)
An 8-week self-administered virtual reality program provides clinically meaningful improvements in pain intensity and interference for adults with chronic low back pain compared to a sham control.
Maddox et al. (2023) conducted an RCT in chronic low back pain (n=1,067). RelieVRx vs. active Sham was evaluated on pain intensity (MD 0.406, 95% CI 0.170-0.642). An 8-week in-home virtual reality program (RelieVRx) was superior to an active sham for reducing pain intensity (MD 0.406; 95% CI 0.170-0.642) and pain interference at day 56.
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