Key result
18F-FDG PET/CT imaging successfully identified a hypermetabolic malignant right renal spindle cell tumor with a tumor thrombus extending through the inferior vena cava into the right atrium.
Case Report (n=1)
No
18F-FDG PET/CT imaging can effectively identify tumor thrombus extension into the IVC and right atrium, differentiating it from benign bland thrombus.
May aid thrombus differentiation in rare renal tumors; hypothesis-generating and requires prospective validation.
Tumor thrombus (also called intravascular tumor extension) can be defined as tumor extending into vessel; typically a vein, it occurs in a lot of malignancies like hepatocellular carcinoma, Wilms tumor, and others.1 Tumor thrombus has been reported to demonstrate increase in fluorine-18 fluorodeoxyglucose (FDG) uptake that would differentiate it from the benign bland thrombus which would not take up FDG on positron emission tomography/computed tomography (PET/CT) scan.1 We present a case of spindle cell sarcoma of right kidney whose baseline contrast-enhanced CT revealed a mass replacing the right kidney and right renal vein associated with thrombus in the inferior vena cava (IVC). 18F-FDG PET/CT imaging was done that revealed an FDG-avid hypermetabolic malignant right renal mass with hypermetabolic IVC thrombus extending to the right atrium.
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Sweedat et al. (2022) conducted a case report in Renal Spindle Cell Tumor with Tumor Thrombus (n=1). 18F-FDG PET/CT was evaluated on Detection and staging of tumor thrombus. 18F-FDG PET/CT imaging successfully identified a hypermetabolic malignant right renal spindle cell tumor with a tumor thrombus extending through the inferior vena cava into the right atrium.
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