Key result
F-18 FDG PET/CT successfully identified an inferior vena cava tumour thrombus in a patient with nonseminomatous germ cell tumour, demonstrating its utility in differentiating tumour from benign thrombus.
Why the study?
Does F-18 FDG PET/CT detect and differentiate tumour thrombus in a patient with nonseminomatous germ cell tumour?
Case Report (n=1)
No
Does F-18 FDG PET/CT detect and differentiate tumour thrombus in a patient with nonseminomatous germ cell tumour?
F-18 FDG PET/CT is useful for identifying and differentiating tumour thrombosis from benign thrombus in patients with nonseminomatous germ cell tumours.
May aid FDG PET/CT differentiation of tumour thrombus in germ cell tumours; hypothesis-generating, requires prospective validation before adoption.
21-year-old male presented with recently diagnosed metastatic nonseminomatous germ cell tumour and left orchidectomy. CT demonstrated mixed density in the inferior vena cava (IVC) extending from the union of the common iliac veins to the level of the liver just below the confluence of the hepatic veins. Retroperitoneal nodal disease and deposits in the left lung were suspicious for metastatic deposits. F-18Flurodeoxyglucose (FDG) PET/CT images demonstrated avid FDG uptake within the lumen of the IVC from the level of the renal veins, with extension into both renal veins, to the level of T10. While benign and malignant thrombi have previously been demonstrated on F18-FDG PET imaging, this case highlights the use of F-18 FDG PET/CT when identifying tumour thrombosis in patients with nonseminomatous germ cell tumour.
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Kearney et al. (2013) conducted a case report in Nonseminomatous germ cell tumour with inferior vena cava tumour thrombus (n=1). F-18 FDG PET/CT was evaluated on Detection and differentiation of tumour thrombus. F-18 FDG PET/CT successfully identified an inferior vena cava tumour thrombus in a patient with nonseminomatous germ cell tumour, demonstrating its utility in differentiating tumour from benign thrombus.
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