Key result
FDG-PET/CT detects occult gonadal vein tumor thrombus, preventing unnecessary surgery in testicular lymphoma.
Why the study?
Tumour thrombus is a rare complication in many solid cancers and lymphoma, and recognition by 18F-FDG PET/CT can change management and prevent misdiagnosis.
Case Report (n=1)
Tumour thrombus is a rare complication of many solid cancers including renal cell carcinoma, Wilms' tumour, testicular tumour, adrenal cortical carcinoma, lymphoma, pancreatic cancer, osteosarcoma and Ewing's sarcoma. We describe six patients who harboured occult tumour thrombus detected by fluorine-18 fluorodeoxyglucose (F-FDG) positron emission tomography (PET)/X-ray computerized tomography (CT) imaging as part of the staging investigations. Recognition of this rare complication by PET/CT can change the management plan and prevent unnecessary long-term anti-coagulation treatment because of wrong diagnosis of cancer-related venous thrombus.
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Bomanji et al. (2007) conducted a case report in Primary testicular diffuse large B-cell lymphoma with gonadal vein tumor thrombus (n=1). 18F-FDG-PET/CT imaging was evaluated. 18F-FDG-PET/CT imaging successfully detected a rare occult gonadal vein tumor thrombus in a patient with primary testicular diffuse large B-cell lymphoma, guiding staging and preventing unnecessary surgical interventions.
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