Key result
F-18 FDG PET/CT successfully detected renal vein and inferior vena cava tumour thrombosis in two patients with renal cell carcinoma.
Why the study?
Does F-18 FDG PET/CT detect renal vein and IVC tumour thrombosis in patients with renal cell carcinoma?
Case Report (n=2)
Does F-18 FDG PET/CT detect renal vein and IVC tumour thrombosis in patients with renal cell carcinoma?
F-18 FDG PET/CT can be a useful imaging modality for the preoperative assessment and detection of renal vein and IVC tumour thrombosis in patients with renal cell carcinoma.
May support preoperative assessment in RCC with suspected thrombosis; hypothesis-generating pending larger prospective validation.
Tumour thrombosis is a relatively rare complication of solid cancers, with occult inferior vena cava(IVC) tumour thrombosis having a reported incidence rate of 0.11%. Renal cell carcinoma(RCC) has a propensity to extend as tumour thrombus into the renal vein and IVC. The preoperative assessment for the presence and extent of renal vein and IVC tumour thrombus is important for planning appropriate surgical resection. There are reports having described the diagnosis of tumour thrombosis by Fluorine-18 fluorodeoxyglucose positron emission tomography and Computed tomography (F-18 FDG PET/CT). We present two cases, one with right RCC showing renal vein and IVC tumour invasion and another left RCC with renal vein, IVC and hepatic vein thrombosis detected using FDG PET/CT.
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Kamaleshwaran et al. (2014) conducted a case report in Renal cell carcinoma with tumour thrombosis (n=2). F-18 FDG PET/CT was evaluated on Detection of renal vein and inferior vena cava tumour thrombosis. F-18 FDG PET/CT successfully detected renal vein and inferior vena cava tumour thrombosis in two patients with renal cell carcinoma.
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