Why the study?
Does genetic liability for PTSD affect CAD risk, and does CAD genetic liability affect PTSD severity?
Observational
Yes
Does genetic liability for PTSD affect CAD risk, and does CAD genetic liability affect PTSD severity?
Answers are grounded in this paper and cite their sources.
Mendelian randomization reveals a bidirectional relationship where genetic liability for PTSD increases CAD risk, while CAD genetic liability is associated with reduced PTSD symptom severity.
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C. E. Mogensen (1998) conducted an observational in Coronary artery disease (CAD) and posttraumatic stress disorder (PTSD). Genetically-determined PTSD symptom severity was evaluated on Coronary artery disease risk (OR 1.04, 95% CI 1.01-1.06).
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