Key result
High levels of TSP1+/CD142+ platelet-derived microparticles characterise young patients with high cardiovascular risk and subclinical atherosclerosis.
Why the study?
Do young patients with high cardiovascular risk have higher levels of prothrombotic circulating microparticles that correlate with subclinical atherosclerosis?
Population
Young patients with high cardiovascular risk, including familial hypercholesterolaemia, and…
Design
Case-control
Authors
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Guideline lipid-lowering insufficiently curbs lymphocyte-derived cMP shedding in FH; leaves open whether adjunctive anti-inflammatory strategies are warranted.
Do young patients with high cardiovascular risk have higher levels of prothrombotic circulating microparticles that correlate with subclinical atherosclerosis?
Prothrombotic circulating microparticles are elevated in young patients with high cardiovascular risk and correlate with subclinical lipid-rich atherosclerotic plaque burden.
Suades et al. (2015) studied High cardiovascular risk and subclinical atherosclerosis. High levels of TSP1+/CD142+ platelet-derived microparticles was evaluated. High levels of TSP1+/CD142+ platelet-derived microparticles characterise young patients with high cardiovascular risk and subclinical atherosclerosis.
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