Key result
A textile heart valve prosthesis prototype was manufactured and its in vitro hydrodynamic performance was evaluated using a pulse duplicator simulating the left side of the human circulatory system.
Why the study?
How does the hydrodynamic performance of a textile heart valve prosthesis prototype compare to commercially available heart valves in an in vitro model?
How does the hydrodynamic performance of a textile heart valve prosthesis prototype compare to commercially available heart valves in an in vitro model?
A textile heart valve prosthesis prototype was manufactured and its in vitro hydrodynamic performance was evaluated against commercial valves.
Textile valve prototype meets in vitro criteria; leaves open feasibility for fabric-based prostheses pending in vivo validation.
A textile heart valve prosthesis is manufactured by forming fabric in such a way as to obtain a valve geometry close to that of the native valve. The forming process leads to optimal closing geometry and limited deformation of the fabric structure during manufacture. The hydrodynamic performance of a fabric heart valve prototype is measured and compared with other commercially available heart valve prosthesis types. In vitro performance of the prototype is evaluated using a pulse duplicator simulating the left side of the human circulatory system, with a 70 ml cardiac output at a constant heart rate of 70 beats/min under a mean diastolic pressure of 100 Hg mm.
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Heim et al. (2008) studied this question. Textile heart valve prosthesis prototype vs. Other commercially available heart valve prosthesis types was evaluated on Hydrodynamic performance. A textile heart valve prosthesis prototype was manufactured and its in vitro hydrodynamic performance was evaluated using a pulse duplicator simulating the left side of the human circulatory system.
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