Key result
Albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) showed high rank-order correlations with 24-hour urinary albumin excretion (r=0.816-0.949), serving as acceptable alternatives.
Why the study?
Are albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) acceptable alternatives to 24-hour urinary albumin excretion (UAE) in epidemiologic studies?
Observational (n=4,678)
Yes
Are albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) acceptable alternatives to 24-hour urinary albumin excretion (UAE) in epidemiologic studies?
Effect estimate: Rank-order correlation 0.949 (men) and 0.942 (women) for ACR; 0.881 (men) and 0.816 (women) for UAC
UAC and ACR are acceptable alternatives to 24-hour urinary albumin excretion in epidemiologic studies, with UAC potentially preferable to ACR due to less confounding by creatinine levels.
No takes yet. Share an insight, caveat, or question.
May simplify albuminuria assessment in epidemiologic studies; leaves open outcome prediction equivalence.
Alan R. Dyer (2004) reported an observational. Albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) vs. 24-hour urinary albumin excretion (UAE) was evaluated on Correlation with 24-hour urinary albumin excretion (UAE) (Rank-order correlation 0.949 (men) and 0.942 (women) for ACR; 0.881 (men) and 0.816 (women) for UAC). Albumin:creatinine ratio (ACR) and urinary albumin concentration (UAC) showed high rank-order correlations with 24-hour urinary albumin excretion (r=0.816-0.949), serving as acceptable alternatives.
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