Key result
Feature-tracking cardiac CT matches cardiac MRI for detecting LGE using GCS and GLS.
Why the study?
This study aimed to validate feature-tracking cardiac CT for left ventricular strain assessment against cardiac MRI in pediatric acute myocarditis, evaluating its potential when cardiac MRI is delayed after clinically indicated coronary CT angiography.
Does feature-tracking cardiac CT provide comparable left ventricular strain assessment to cardiac MRI in children with acute myocarditis?
Comparison
FT-CCT vs CMR
Design
Validation study
Authors
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May offer pragmatic FT-CCT strain assessment in pediatric myocarditis when CMR is delayed; leaves open routine CMR replacement.
Observational (n=45)
Does feature-tracking cardiac CT provide comparable left ventricular strain assessment to cardiac MRI in children with acute myocarditis?
Effect estimate: AUC 0.716 vs 0.718
p-value: p=0.974
Feature-tracking cardiac CT is a reproducible and robust alternative to cardiac MRI for assessing left ventricular strain and detecting myocardial injury in pediatric acute myocarditis.
Yang et al. (2026) conducted an observational in pediatric acute myocarditis (n=45). Feature-tracking cardiac CT (FT-CCT) vs. Cardiac MRI (CMR) was evaluated on Diagnostic performance for detecting late gadolinium enhancement (LGE) using global circumferential strain (GCS) (AUC 0.716 vs 0.718, p=0.974). Feature-tracking cardiac CT demonstrated diagnostic performance equivalent to cardiac MRI for detecting late gadolinium enhancement using GCS (AUC 0.716 vs 0.718, P=0.974) and GLS.
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