Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 23, 2026European journal of psychotraumatologyOpen Access

Integrated exposure-based therapy for co-occurring post-traumatic stress and substance use among young people: a randomized controlled trial

View Full Paper
Ask AI
Bookmark
Share

Authors

KMKatherine L. MillsNPN PeachIKIvana Kihas

Discussion

Loading...

Member takes

Overview

Randomized trial compares integrated treatment for PTSD and substance use among young people, indicating its superior efficacy over supportive counseling.

Key Points

  • This trial aims to compare the efficacy of an integrated therapy for PTSD and substance use disorder among young people with a supportive counseling control.
  • Randomized controlled trial with 55 participants aged 12–25 recruited in Sydney, Australia.
  • Participants were assigned to either the COPE-A therapy or person-centered therapy (PCT).
  • PTSD and substance use outcomes were measured at study entry, 4 months, and 12 months.
  • COPE-A produced a significant reduction in PTSD symptom severity with a mean difference of −9.82 (95% CI −16.11 to −3.53).
  • Significantly lower odds of PTSD diagnosis in the COPE-A group (odds ratio = 0.06, 95% CI 0.01 to 0.46).
  • Increased client satisfaction with COPE-A compared to PCT, and no adverse events reported.

Cite This Study

Mills et al. (2026) studied this question.

synapsesocial.com/papers/6a61afaefaa9903c5116a6b1https://doi.org/10.1080/20008066.2026.2691364
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrated treatment of posttraumatic stress disorder and substance use disorders for adolescents and youth: current evidence and future directions2026
  2. 2Massed prolonged exposure for posttraumatic stress disorder among individuals in comprehensive substance use treatment: Study protocol for a randomized controlled trial2026
  3. 3Clinical characteristics of adolescents and emerging adults presenting for integrated posttraumatic stress and substance use treatment2024
  4. 4Implementing Prolonged Exposure Therapy in a Community Substance Use Treatment Program: A Qualitative Study2026
  5. 5Protocol for a feasibility study, without control group, of a combined treatment for PTSD and difficulties in emotion regulation for patients with substance use disorder2026