TLMM v8.0 — From First Verified Cell to First Verified Panel: A Transparent Framework for Independent Panel Verification and Community Reproduction

TLMM v8.0 extends the Transparent Layered Medical Model (TLMM) from the first verified cell (v7.9) to the first verified panel through a transparent, independently reproducible verification framework. The framework integrates a parallel verification engine, prospectively locked protocols and datasets, automated re-execution, reproducibility capsules, a cryptographically signed evidence ledger, distributed independent auditing, and a governance framework. Verification progresses through a unified seven-state evidence model (State 0–6), with every transition being evidence-based, cryptographically verifiable, and publicly auditable. The representative five-cell pilot demonstrates the framework using clearly separated reporting populations to avoid denominator conflation:• Pilot (Current): 3/5 verified (60%)• Pilot (Final, illustrative target): 5/5 verified (100%)• Historical Registry: 753/1,256 verified (60%)• Community Reproduction: 1,003/1,118 (89.7%) Roadmap-scale and large-scale verification figures are explicitly labeled as representative or illustrative design targets. This Zenodo deposit contains:• Full manuscript (30 pages)• 26 embedded figures• 26 source figures (PNG)• README• CITATION.cff• LICENSE (CC BY 4.0)• Zenodo metadata files Author:Koji OkinoSD Lab LLCORCID: 0009-0003-9273-9813