Why the study?
Hypertension is prevalent in chronic kidney disease and drives cardiovascular complications and renal dysfunction, but real-world antihypertensive prescribing patterns needed evaluation to optimize blood pressure management.
Does antihypertensive therapy improve blood pressure and serum creatinine in adults with chronic kidney disease and hypertension?
Population
100 adults with CKD and hypertension attending a tertiary-care teaching hospital
Design
Prospective observational study
Key result
Antihypertensive therapy was associated with significant reductions in systolic blood pressure (160.13 to 134.20 mmHg), diastolic blood pressure, and serum creatinine over 6 months (all p<0.001).
Authors
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Prescribing patterns in advanced CKD merit review in practice; leaves open optimal regimens and outcomes pending controlled trials.
Observational (n=100)
No
Does antihypertensive therapy improve blood pressure and serum creatinine in adults with chronic kidney disease and hypertension?
p-value: p=<0.001
In a real-world cohort of patients with advanced CKD and hypertension, treatment predominantly with diuretics and calcium channel blockers was associated with significant improvements in blood pressure and serum creatinine over 6 months.
Rehman et al. (2026) conducted an observational in Chronic kidney disease and hypertension (n=100). Antihypertensive therapy was evaluated on Changes in systolic blood pressure, diastolic blood pressure, and serum creatinine (p=<0.001). Antihypertensive therapy was associated with significant reductions in systolic blood pressure (160.13 to 134.20 mmHg), diastolic blood pressure, and serum creatinine over 6 months (all p<0.001).
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