Study of Antihypertensive Drug Utilization Pattern in Chronic Kidney Disease Patients

Introduction: Hypertension is a chronic illness associated with high morbidity & mortality, with a rising number of patients with hypertension and chronic kidney disease, achieving blood pressure of less than 140/90 mm of Hg is challenging.Hence, there is a need for appropriate, safe, effective and economical study to find out the patterns of drug therapy.Objectives: To evaluate utilization patterns of antihypertensive agents in chronic kidney disease patients.Methodology: A prospective observational study was conducted for a period of 6 months in Jayanagar General Hospital, Bengaluru.We included 70 hypertensive CKD patients.Detailed patient information data were noted, and data entered in a preformed proforma in Microsoft Excel sheet for compilation and subjected to statistical analysis.Results: Total 70 case records of patients having chronic kidney disease were analysed.Mean age was 52.08 ± 15.14.CKD was more prevalent in males 38 (54.2%) and 32 (46.8%) females with male to female ratio of 2.3:2.Most of the patients (52.80%) belonged tote age group of 41-60 years.Among the anti-hypertensive agents, most frequently used was calcium channel blockers (91.4%), followed by diuretics (54.2%),Beta blockers (31.4%), alpha blockers, ACE inhibitors and ARB.Conclusion: Dual and triple therapy were prescribed which was according to ESH guidelines.This study highlights some therapeutic rationality in this health centre.However,