Key result
Obesity (prevalence 25.2%) in persons with older-onset diabetes was not associated with the long-term incidence of microvascular and macrovascular complications.
Why the study?
Does obesity increase the incidence of microvascular and macrovascular complications in patients with older-onset diabetes?
Cohort (n=1,370)
No
Does obesity increase the incidence of microvascular and macrovascular complications in patients with older-onset diabetes?
In patients with older-onset diabetes, obesity is not associated with an increased long-term incidence of microvascular and macrovascular complications, whereas being underweight is associated with higher mortality and stroke risk.
No takes yet. Share an insight, caveat, or question.
Obesity may not independently drive complications in older-onset diabetes; leaves open need for updated prospective data.
Ronald Klein (1997) conducted a cohort in Diabetes (n=1,370). Obesity vs. Normal weight was evaluated on Incidence and progression of retinopathy, gross proteinuria, lower-extremity amputation, and mortality (ischemic heart disease, stroke, all-cause). Obesity (prevalence 25.2%) in persons with older-onset diabetes was not associated with the long-term incidence of microvascular and macrovascular complications.
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