Key result
Placement of acrylic cement during total hip replacement induced mild cardiovascular depression that was not statistically significant (p>0.05).
Why the study?
Does total hip placement with acrylic cement and methylmethacrylate exposure cause cardiovascular depression?
Population
10 surgical patients aged 55 to 82 undergoing total hip placement, and 24 isolated perfused rabbit hearts.
Design
Other
Follow-up
acute/intraoperative
Authors
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Mild nonsignificant depression during cement placement supports no practice change; leaves open dose-dependent risks for prospective study.
Observational (n=10)
Does total hip placement with acrylic cement and methylmethacrylate exposure cause cardiovascular depression?
p-value: p=>0.05
Methylmethacrylate used in total hip placement can cause dose-dependent myocardial depression and bradycardia, which may be mitigated by pacing or atropine.
Wong et al. (1977) conducted an observational in Total hip placement (n=10). Placement of acrylic cement (methyl methacrylate) was evaluated on Cardiovascular depression (p=>0.05). Placement of acrylic cement during total hip replacement induced mild cardiovascular depression that was not statistically significant (p>0.05).
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