Key result
Tissue factor exposure upon plaque rupture plays a pivotal role in mediating fibrin-rich thrombus formation leading to acute coronary syndromes.
Design
Review
Authors
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Supports TF's central role in ACS thrombosis; hypothesis-generating for targeted inhibition, needs prospective trials.
This review highlights the critical pathophysiological role of tissue factor in arterial thrombosis and acute coronary syndromes.
Asada et al. (1998) conducted a review in Thrombosis and Atherosclerosis. Tissue Factor was evaluated. Tissue factor exposure upon plaque rupture plays a pivotal role in mediating fibrin-rich thrombus formation leading to acute coronary syndromes.
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