Population
Patients with acute coronary syndromes
Design
Review
Authors
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Potential prothrombotic effects of thrombolysis via TFPI degradation warrant clinical caution in ACS; leaves open TF/TFPI-targeted therapies for prospective trials.
This review outlines the pathophysiological role of tissue factor and its regulation by TFPI in acute coronary syndromes, noting the potential for a prothrombotic state following therapeutic thrombolysis.
Ilka Ott (2003) studied this question.
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