Key result
Among 8 infants with human parechovirus infection, 5 presented with prominent abdominal distension and 6 with an erythematous rash, clinical signs that can mimic acute surgical conditions.
Why the study?
What are the clinical features of human parechovirus infection in infants presenting with sepsis-like illness?
Observational (n=8)
What are the clinical features of human parechovirus infection in infants presenting with sepsis-like illness?
A combination of red rash, abdominal distension, low CRP, and low lymphocyte count can be important clues for recognizing human parechovirus infection in infants with sepsis-like illness.
Answers are grounded in this paper and cite their sources.
May prompt HPeV testing in infants with abdominal distension and rash; leaves open larger studies before changing practice.
A total of 8 infants presenting with sepsis-like illness were diagnosed to have human parechovirus (HPeV) infection; of which, 5 had abdominal distension and 6 had an erythematous rash. A combination of abdominal distension and erythematous rash was observed in 4 infants. The abdominal symptoms can be very prominent and signs could be confused with acute surgical conditions. Although fever and central nervous symptoms are important features, a red rash with abdominal distension and a low C-reactive protein value and lymphocyte count can be clues to recognize this infection.
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Bangalore et al. (2011) conducted an observational in Human parechovirus (HPeV) infection (n=8). Human parechovirus (HPeV) infection was evaluated on Clinical features including abdominal distension and erythematous rash. Among 8 infants with human parechovirus infection, 5 presented with prominent abdominal distension and 6 with an erythematous rash, clinical signs that can mimic acute surgical conditions.
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