Key result
Human parechovirus-3 infection can present with a gastrointestinal phenotype featuring severe abdominal distention that mimics Hirschsprung-associated enterocolitis in pre-term infants.
Human parechovirus-3 infection can present with a gastrointestinal phenotype mimicking Hirschsprung-associated enterocolitis in pre-term infants.
Consider human parechovirus-3 in preterm infants with enterocolitis-like distention; single case leaves association hypothesis-generating.
Human parechovirus-3 (HPeV-3) infection is being increasingly identified as an important pathogen leading to neonatal sepsis-like illness. In this case report, we present a pre-term infant with striking abdominal distention whose signs and symptoms were quite similar to those of Hirschsprung-associated enterocolitis but the patient suffered from the gastrointestinal phenotype of HPeV-3 infection.
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Watanabe et al. (2014) studied this question. Human parechovirus-3 infection can present with a gastrointestinal phenotype featuring severe abdominal distention that mimics Hirschsprung-associated enterocolitis in pre-term infants.
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