Key result
Adolescents with type 1 diabetes had impaired nerve conduction velocity compared to controls, with 10 of 100 patients showing distal diabetic polyneuropathy neurophysiologically.
Why the study?
Does puberty impact peripheral nerve function in adolescents with type 1 diabetes compared to healthy controls?
Population
100 adolescents with type 1 diabetes and 100 age- and sex-matched healthy control subjects
Design
Cross-sectional
Authors
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May warrant puberty-stage neuropathy surveillance in type 1 diabetes; leaves open need for longitudinal studies before screening changes practice.
Cross-Sectional (n=200)
No
Does puberty impact peripheral nerve function in adolescents with type 1 diabetes compared to healthy controls?
Subclinical motor and sensory nerve impairment increases during late puberty in adolescents with type 1 diabetes, associated with poor metabolic control.
Riihimaa et al. (2001) conducted a cross-sectional in Type 1 diabetes (n=200). Type 1 diabetes during puberty vs. Age- and sex-matched healthy controls was evaluated on Peripheral nerve function (motor and sensory nerve conduction, cardiovascular reflex, vibration-perception threshold). Adolescents with type 1 diabetes had impaired nerve conduction velocity compared to controls, with 10 of 100 patients showing distal diabetic polyneuropathy neurophysiologically.
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