November 1, 2002Diabetic Medicine
Cardiovascular autonomic reactivity is decreased in adolescents with Type 1 diabetes
Why the study?
Is cardiovascular autonomic reactivity decreased in adolescents with Type 1 diabetes compared to healthy controls?
Population
100 adolescent patients with Type 1 diabetes mellitus from an out-patient clinic and 100 healthy control…
Design
Case-control
Authors
Discussion
Loading...
Member takes
Implication
Supports hypothesis of early subclinical autonomic dysfunction in adolescent T1D; hypothesis-generating and requires prospective validation before clinical adoption.
Structured PICO
Is cardiovascular autonomic reactivity decreased in adolescents with Type 1 diabetes compared to healthy controls?
P
Population
100 adolescent patients with Type 1 diabetes mellitus from an out-patient clinic and 100 healthy control subjects.
C
Comparator
Healthy control subjects
O
Outcome
Cardiovascular autonomic reactivity (heart rate and blood pressure responses at rest, during deep breathing, and standing; heart rate variability)surrogate
Adolescents with Type 1 diabetes exhibit attenuated cardiovascular autonomic reactivity upon standing, indicating early subclinical autonomic dysfunction.
Cite This Study
Riihimaa et al. (2002) studied this question.