Key result
Type 1 diabetes in children and young adults was associated with significantly lower beat-to-beat blood pressure fluctuation compared to healthy controls, with abnormalities present in 12% of patients.
Why the study?
Does Type 1 diabetes mellitus affect autonomic function in asymptomatic children and young adults compared to healthy controls?
Population
58 asymptomatic children and young adults with Type 1 diabetes mellitus and 74 healthy controls.
Design
Case-control
Authors
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May signal early autonomic changes in asymptomatic T1D youth; leaves open prognostic value and screening utility.
Case-Control (n=132)
Does Type 1 diabetes mellitus affect autonomic function in asymptomatic children and young adults compared to healthy controls?
In asymptomatic children and young adults with Type 1 diabetes, vagal neuropathy is uncommon, but early autonomic dysfunction may manifest as reduced beat-to-beat blood pressure variation that correlates with metabolic control.
Tanaka et al. (1998) conducted a case-control in Type 1 diabetes mellitus (n=132). Type 1 diabetes mellitus vs. Healthy controls was evaluated on Abnormal beat-to-beat blood pressure fluctuation. Type 1 diabetes in children and young adults was associated with significantly lower beat-to-beat blood pressure fluctuation compared to healthy controls, with abnormalities present in 12% of patients.
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