Key result
In 60 symptomatic patients, 256-slice CT coronary angiography demonstrated high sensitivity and specificity compared to invasive angiography for detecting coronary artery stenosis.
Why the study?
The study was conducted to evaluate the diagnostic accuracy of 256-slice CT coronary angiography in measuring percentage diameter stenosis compared to invasive angiography in symptomatic patients.
Does 256-slice CT coronary angiography accurately detect coronary artery stenosis compared to invasive angiography in patients with chest pain and risk for CAD?
Cross-Sectional (n=60)
No
Does 256-slice CT coronary angiography accurately detect coronary artery stenosis compared to invasive angiography in patients with chest pain and risk for CAD?
256-slice CCTA is a highly accurate and rapid initial diagnostic test for evaluating coronary artery stenosis in patients with chest pain and low-to-intermediate CAD risk.
Supports 256-slice CCTA accuracy for stenosis detection; leaves open its impact on management versus invasive angiography.
Coronary Artery Disease (CAD) is an emerging and commonest type of heart disease resulting in morbidity and mortality globally. Coronary angiography is a diagnostic modality used to diagnose the coronary artery disease or the extent of blockage of coronary arteries. The multi-slice computed tomography (MSCT) technology such as 64-slice, 128-slice, 256-slice, and now 320-slice MSCT has produced a high diagnostic accuracy of CT coronary angiography. This prospective-cross sectional study was done in Department of Cardiology in Medanta, the Medicity, from November 2017 to December 2018 with the aim to evaluate the diagnostic accuracy of 256 slice CT coronary angiogram in measuring the percentage diameter stenosis compared to invasive angiography and to determine the sensitivity and specicity of CT coronary angiography in detection of coronary artery stenosis among symptomatic patients. A total of 60 patients presented with acute or chronic chest pain with risk for CAD were included. The mean age of the participants was 57.35±10.16 years and 88.3% participants were male and 11.7% participants were females. 56.6% participants had BMI >25, 11.7% were alcoholic, 40% were smoker, 16.7% had diabetes and 38.3% had hypertension. The study concluded that CCTA should be considered initial test of choice in patients presenting with chest pain with low to intermediate probability of CAD because the time required for diagnosis is signicantly shorter, high sensitivity, specicity, PPV and NPV on per vessel and per segment basis, determination of LVEF and has the ability to rule out causes of atypical chest pain including pulmonary embolism and aortic dissection.
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Saqib et al. (2022) conducted a cross-sectional in Chest pain with risk for Coronary Artery Disease (n=60). 256-slice CT coronary angiography vs. Invasive angiography was evaluated on Diagnostic accuracy (sensitivity and specificity) in detecting coronary artery stenosis. In 60 symptomatic patients, 256-slice CT coronary angiography demonstrated high sensitivity and specificity compared to invasive angiography for detecting coronary artery stenosis.
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