Key result
Backward pressure wave amplitude and carotid-femoral pulse wave velocity were significant independent predictors of orthostatic hypotension in both younger and older subjects.
Why the study?
Are wave reflections and arterial stiffness associated with orthostatic hypotension and orthostatic blood pressure changes?
Population
613 subjects who participated in hemodynamic studies
Comparison
Higher backward pressure wave amplitude and… vs Lower backward pressure wave amplitude and…
Design
Cross-sectional
Authors
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May aid orthostatic hypotension risk stratification; leaves open clinical utility pending validation.
Cross-Sectional (n=613)
Are wave reflections and arterial stiffness associated with orthostatic hypotension and orthostatic blood pressure changes?
Wave reflections and arterial stiffness are independent determinants of orthostatic systolic blood pressure change and orthostatic hypotension in both younger and older subjects.
Sung et al. (2014) conducted a cross-sectional in Orthostatic hypotension (n=613). Backward pressure wave amplitude (Pb) and carotid-femoral pulse wave velocity (cf-PWV) was evaluated on Orthostatic hypotension (fall of ≥20 mm Hg in SBP and/or ≥10 mm Hg in DBP). Backward pressure wave amplitude and carotid-femoral pulse wave velocity were significant independent predictors of orthostatic hypotension in both younger and older subjects.
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