Key result
Pindolol 15 mg/day eliminated orthostatic symptoms and maintained standing blood pressure above 90/50 mm Hg in three patients with severe orthostatic hypotension.
Why the study?
Does pindolol improve orthostatic symptoms and hemodynamics in patients with severe orthostatic hypotension due to chronic autonomic failure?
Population
3 bedridden patients with severe orthostatic hypotension due to chronic autonomic failure
Design
Case_series
Authors
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May permit ambulation in severe autonomic orthostatic hypotension; leaves open confirmation in controlled trials.
Case Report (n=3)
Does pindolol improve orthostatic symptoms and hemodynamics in patients with severe orthostatic hypotension due to chronic autonomic failure?
Pindolol, acting as a partial beta-adrenoceptor agonist, may be an effective treatment for severe orthostatic hypotension in patients with chronic autonomic failure.
Veld et al. (1981) conducted a case report in Severe orthostatic hypotension due to chronic autonomic failure (n=3). Pindolol was evaluated on Orthostatic symptoms and hemodynamic parameters. Pindolol 15 mg/day eliminated orthostatic symptoms and maintained standing blood pressure above 90/50 mm Hg in three patients with severe orthostatic hypotension.
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